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Arkistoitu opetusohjelma 2016–2017
Selaat vanhentunutta opetusohjelmaa. Voimassa olevan opetusohjelman löydät täältä.
KEMI6409 LC-MS and its applications 5 ECTS
Periods
Period I Period II Period III Period IV
Language of instruction
English
Type or level of studies
Advanced studies
Course unit descriptions in the curriculum
Kemia
Department of Chemistry

Learning outcomes

The student knows the theory of liquid chromatography and mass spectrometry and the practical factors related to their use. The student is able to describe the most common LC-MS methods used and knows where and how these methods can be applied. The student knows how to perform an LC-MS-analysis.

General description

The course gives good basic information about the liquid chromatography (LC) and mass spectrometry (MS) and especially about the hyphenated techniques (LC-MS). The course introduces the instruments, eluents and columns most commonly used in the liquid chromatography. Furthermore, the sample preparation and chromatographic performance is discussed. The main emphasis of this course is on the mass spectrometry, where the different ionization techniques and mass analyzers are presented and the tandem mass spectrometry explored. The practical examples and case studies create an overview of the suitability of LC-MS methods for the qualitative and quantitative analysis of different-type analytes. The course includes a laboratory work where LC-MS analyses are performed utilizing ultra-high performance liquid chromatographs combined with electrospray ionization triple quadrupole and orbitrap mass spectrometers.

Teacher responsible

Maarit Karonen

Teaching

6-Mar-2017 – 28-Apr-2017
Lectures 28 h
Mon 6-Mar-2017 - 10-Apr-2017 weekly at 12-14, ARC 3
Thu 9-Mar-2017 - 6-Apr-2017 weekly at 14-16, ARC 3
Thu 20-Apr-2017 at 14-16, ARC 3
Mon 24-Apr-2017 at 12-14, ARC 3
Fri 28-Apr-2017 at 10-12, ARC 3
Exercises 4 h

Evaluation

Numeric 0-5.

Evaluation criteria

Participation in the laboratory work and a written report, written exam in English or Finnish

Incoming examinations