Uusi opinto-opas (sisältäen myös opetusohjelmat) lukuvuodelle 2018-2019 sijaitsee osoitteessa https://opas.peppi.utu.fi . Tältä sivustolta löytyvät enää vanhat opinto-oppaat ja opetusohjelmat.

The new study guide (incl. teaching schedules) for academic year 2018-2019 can be found at https://studyguide.utu.fi. This site contains only previous years' guides.

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Archived Curricula Guide 2014–2016
Curricula Guide is archieved. Please refer to current Curricula Guides
BIOI4301 Basic X-Ray Crystallography Techniques: How to Solve a Protein Structure 3 ECTS
Organised by
Person in charge
Tassos Papageorgiou

General description

This course is arranged by Turku Centre for Biotechnology.

Learning outcomes

The aim of the course is to familiarize students and experienced researchers with the various crystallographic programs used in the determination of protein structures. By the end of the course, it is expected that the participants will be able to solve the crystal structure of a simple protein using X-ray crystallography techniques and understand the terminology used in publications.


The course consists of lectures, demonstrations and practicals of all major steps in a crystal structure determination - from crystallization and data collection to computational techniques and the final structure. Key crystallographic programs include MOSFLM for data processing, CCP4i for data handling and automated building, PHASER for molecular replacement, PHENIX for experimental phasing and refinement, COOT for visualization of the structures, manual rebuilding, and validation.

Teaching methods

Teaching method Contact Online
Lectures 3 h 0 h
Exercises 17 h 0 h

Teaching language


Modes of study

Exercises, exam


Numeric 0-5.

Recommended year of study

1. year spring

Belongs to following study modules

Department of Future Technologies
Department of Future Technologies
Archived Teaching Schedule. Please refer to current Teaching Shedule.
Implementation details are unavailable.
Department of Future Technologies
DP in Computer Science
DP in Computer Science
DP Bachelor of Science in Techn.(Communication St)
DP in Information and Communication Technology
Finnish Study Modules