Curricula Guides

Uusi opinto-opas (sisältäen myös opetusohjelmat) lukuvuodelle 2018-2019 sijaitsee osoitteessa https://opas.peppi.utu.fi . Tältä sivustolta löytyvät enää vanhat opinto-oppaat ja opetusohjelmat.

The new study guide (incl. teaching schedules) for academic year 2018-2019 can be found at https://studyguide.utu.fi. This site contains only previous years' guides.

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Archived Curricula Guide 2016–2018
Curricula Guide is archieved. Please refer to current Curricula Guides
DRUG0009 Therapy areas in drug discovery and translational medicine II 6 ECTS
Organised by
Drug Discovery and Development
Person in charge
Markku Koulu

Learning outcomes

The aim of the study module is that students will be able to describe pathophysiological disease mechanisms, diagnostic methods and biomarkers as well as clinical symptoms of diseases in some main therapy areas, such as disorders of the central nervous system (CNS), cancer and oncology, endocrine and metabolic diseases, cardiovascular diseases and immune system disorders. Students must be able to discuss the mechanisms of action of currently used drugs and to critically assess their utility in the treatment of these diseases; they should also understand existing unmet medical needs. Students can explain how animal disease models are produced and employed in the development of new drugs and how translational medicine approaches are used to facilitate the entry of drug candidates into clinical development. In addition, students will be able to analyze patent databases and other sources of information in order to get insight into emerging new drug targets and drug development pipelines in each therapy area. As built-in component, students practice communication skills by preparing scientific presentations for seminars.

Contents

As the entire study module is based on self-guidance of students and group work, only the main topics are given in advance. These include topics from the CNS disease area (such as Alzheimer's disease, Parkinson's disease, depression, addiction, psychosis, multiple sclerosis), endocrine and metabolic diseases (such as diabetes, metabolic syndrome and obesity, dyslipidemias, osteoporosis), cancer and oncology (such as breast cancer, prostate cancer), cardiovascular diseases (such as heart failure, coronary heart disease) and autoimmune diseases (such as rheumatoid arthritis, psoriasis).

Teaching methods

The study module is divided into two parts: This is the 2nd part (endocrinological and metabolic disorders, cardiovascular diseases and autoimmune diseases; DRUG0009 Therapy Areas in Drug Discovery and Translational Medicine II 6 ECTS) during the spring semester (group work 112 h, seminars 28 h, science smeinar week activity 20 h).

Teaching language

English

Modes of study

Students are divided into groups of four or five. Each group will prepare a presentation on the topic of the week, and the groups will present their work in random order at the end of the week. The presentations will have the following subheadings: pathophysiological mechanisms, diagnostic criteria, clinical symptoms, current drug therapy, animal models, emerging new targets and an overview of the pipeline situation. In addition, both in the autumn and spring semester, there will be a science seminar week during which local research groups are presenting their research projects and activities including methodological aspects of their research.

Evaluation and evaluation criteria

Numeric 0-5.
Evaluation criteria are based on: a) knowledge of the entire area of the study module, as measured by a written examination (60 % of the total grade), b) quality of seminar presentations and activity (40 % of the total grade).

Recommended year of study

1. year spring

Study materials

Relevant chapters of textbooks of pathology, pharmacology, internal medicine, endocrine, neurology and immunology. Recent review articles of the topics. Patent databases, pipeline databases of drug discovery companies.

Belongs to following study modules

Institute of Biomedicine
2018–2019
Teaching
Archived Teaching Schedule. Please refer to current Teaching Shedule.
Implementation details are unavailable.
Institute of Biomedicine
DP in Biomedicine
Finnish Study Modules
MDP in Drug Discovery and Development
MDP in Biomedical Imaging
Biomedical Imaging